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Radiesse® Filler
Clinic Cleo®
Radiesse® Filler
Restore Volume, Rebuild Collagen
Radiesse® is an FDA-cleared injectable dermal filler made from calcium hydroxylapatite (CaHA) microspheres suspended in a smooth gel. Unlike fillers that simply add volume, Radiesse also works as a collagen biostimulator — triggering your skin to produce its own new collagen and elastin, for results that improve over time and last up to 12–15 months.
At CLEO Clinic, Radiesse is administered by experienced aesthetic doctors to smooth moderate-to-severe facial folds, restore lost volume, and improve skin quality from within.
















What Is Radiesse
Radiesse is an FDA-approved dermal filler made with calcium hydroxylapatite (CaHA) microspheres suspended in a gel. It restores lost facial volume, smooths moderate to severe wrinkles and folds, and stimulates the body’s natural collagen production for long-lasting skin rejuvenation. Radiesse is commonly used to treat the cheeks, jawline, smile lines, and aging hands, with results that can last up to 18 months or longer in some patients.
How Does Radiesse Work?
Radiesse works in two stages. First, immediate correction: the gel carrier and CaHA microspheres fill in wrinkles, folds, and areas of volume loss the moment it’s injected. Second, biostimulation: over the following weeks, the CaHA microspheres act as a scaffold that encourages your body to generate new collagen and elastin.
As the gel carrier is naturally absorbed, this new collagen gradually takes its place, so results build progressively rather than simply sitting under the skin.
The microspheres are eventually broken down and cleared by the body through normal metabolic processes, making Radiesse fully biodegradable and biocompatible, with a well-documented long-term safety profile.
What Radiesse Treats
Radiesse is commonly used to correct:
- Nasolabial folds (smile lines)
- Marionette lines (mouth corners to chin)
- Cheek volume loss and midface flattening
- Jawline contouring and definition
- Chin augmentation and profile balancing
- Pre-jowl sulcus correction
- Thinning, vein-prominent hands
- Temple hollowing
What to Expect During Treatment
Your CLEO Clinic doctor begins with a facial assessment to map volume loss and build a personalized treatment plan. A topical numbing cream or local anesthetic is applied for comfort, and Radiesse is injected into the subdermal layer using fine needles or cannulas targeting the folds or volume-loss areas. The doctor then gently massages and shapes the product for a smooth, natural contour.
A typical appointment takes 30 to 45 minutes, with minimal downtime — most patients resume normal activities the same day.
Results and How Long Radiesse Lasts
Results typically last 12 to 15 months, depending on the treatment area, individual metabolism, and amount of product used. Areas with more movement, like around the mouth, may see slightly shorter duration than areas like the cheeks or jawline.
Volume correction is visible immediately after injection, while improvements in skin firmness and quality continue over 4 to 8 weeks as new collagen forms.
Why Radiesse Is Trusted
Radiesse received FDA clearance for the correction of moderate to severe facial wrinkles and folds, such as nasolabial folds, and has been studied extensively in long-term clinical literature for its safety, biocompatibility, and durability as a soft-tissue filler. It’s manufactured by Merz Aesthetics, a global leader in aesthetic medicine, and every Radiesse treatment at CLEO Clinic is performed by a qualified, experienced aesthetic doctor.
Radiesse vs. Hyaluronic Acid Fillers
| Radiesse (CaHA) | Hyaluronic Acid Fillers | |
|---|---|---|
| Mechanism | Volumizes and stimulates natural collagen | Volumizes by attracting water |
| Duration | 12–15 months | 6–18 months, varies by product |
| Reversible | Not reversible with hyaluronidase | Reversible with hyaluronidase |
| Best for | Deeper folds, jawline, hands | Lips, fine lines, delicate areas |
Am I a Candidate for Radiesse?
Radiesse may be right for you if you have moderate to severe nasolabial folds or marionette lines, volume loss in the cheeks, jawline, chin, or hands, and want a treatment that also stimulates natural collagen production alongside gradual, progressive improvement.
Radiesse is not recommended for the lips or very thin-skin areas, and is not suitable for patients who are pregnant or breastfeeding, or who have certain bleeding disorders or active skin infections at the injection site. A consultation with your CLEO Clinic doctor will confirm suitability.
5 Key Benefits of
Radiesse Filler

Instant Lift & Contour
Restores volume and sculpts sagging areas like cheeks, jawline, and lower face immediately.
Stimulates Natural Collagen
Powered by Calcium Hydroxylapatite (CaHA) to boost your own collagen for long-term skin quality.
Firms & Tightens Skin
Improves skin laxity, firmness and elasticity from within - not just filling.
Long-Lasting Results
Results can last up to 12-18 months with natural, gradual improvement over time.
Natural-Looking & Biocompatible
Biocompatible formula that integrates naturally with your skin for soft, not overdone, results.
5 Problems Radiesse Filler
Treats That Other Fillers Can't
01
Sagging, Not Just Volume LossHA fillers fill lines - Radiesse actually lifts and re-supports sagging skin.
02
Loss of Firmness & ElasticityIt doesn't just fill, it rebuilds your own collagen to firm loose, lax skin.
03
Weak Jawline & JowlsProvides strong structural support to sharpen the jawline and lift the lower face where soft fillers fall flat.
04
Thin, Crepey Skin QualityImproves skin thickness and texture from within, not just plumping from underneath.
05
Tired Face Despite FillersTargets the root cause - collagen depletion - for a natural, lifted look that doesn't look puffy or overdone.
Long-Term Collagen. Results That Last Up to 2 Years.
Germany Technology
Radiesse Lifts Now And Rebuilds Later
Unlike regular fillers that just add volume, Radiesse is a Calcium Hydroxylapatite (CaHA) collagen biostimulator that gives you an instant contour lift while stimulating your own natural collagen for firmer, more youthful skin over time.
Radiesse vs. Hyaluronic Acid Fillers
Which Fillers Is Right For You?
| Feature | Radiesse | Hyaluronic Acid Fillers |
|---|---|---|
| Main ingredient | Calcium hydroxylapatite (CaHA) | Hyaluronic acid |
| Typical duration | 18-24 months | 6-12 months |
| Collagen stimulation | Yes, significant | Minimal |
| Best suited for | Lifting, firming, deeper folds | Hydration, fine lines, lips |
| Reversible | No | Yes (with hyaluronidase) |
Dr. Raimie
Bin Rahmad
Aesthetic Physician
- Doctor of Medicine (M.D.) – MMA
- Professional Diploma in Aesthetic Medicine
- LCP Accredited by the Ministry of Health (MOH)
- Founder & Medical Director of Cléo Clinic
Dr. Tan
Choy Ling
Aesthetic Physician
- Doctor of Medicine (M.D.) – MMA
- Postgraduate Diploma in Dermatology in Clinical Practice – University of South Wales, UK
- Professional Diploma in Aesthetic Medicine – AAA
- LCP Accredited by the Ministry of Health (MOH)
- Co-Founder of Cléo Clinic
Dr. Seok
Wye Kitt
Aesthetic Physician
- M.D.(RSMU)
- Postgraduate Medical Aesthetic Certification (MAC)
- Medical Aesthetic International Certification (MAIC)
- Clinical Director of Cléo Clinic
- LCP Accredited by MOH
Dr. Amy Lau
Aesthetic Physician
- M.D.(UKM)
- Postgraduate Medical Aesthetic Certification (MAC)
- Certificate in Aesthetic Medicine – American Academy of Aesthetic Medicine (AAAM)
- Professional Diploma in Dermatology – Royal College Of Physician Of Ireland
- LCP Accredited by MOH
- Clinical Director of CLÉO CLINIC Kepong
Dr. Sara
Thong
Aesthetic Physician
- MBBS.(Manipal)
- Professional diploma in Aesthetic Medicine – IIWAM
- Postgraduate Diploma In Dermatology In Clinical Practice – University Of South Wales, UK
- LCP Accredited by MOH
- Clinical Director of CLÉO CLINIC Cheras
Dr. Famey
Lee see kit
Aesthetic Physician
- Bachelor of Medicine & Bachelor of Surgery (MBBS) – Fudan , Shanghai
- Postgraduate Medical Aesthetic Certification (MAC)
- Postgraduate Diploma In Dermatology (AFPM)
- LCP accredited by MOH
Book Your Radiesse
Consultation at CLEO Clinic
If your skin has been looking less firm, sagging, or simply tired lately, Radiesse offers a fast, minimal-downtime way to restore structure, firmness and youthful contours while stimulating your own collagen.
Our LCP-certified medical team will assess your skin and confirm whether Radiesse fits your specific concerns.
Book a consultation with CLEO Clinic to find out if Radiesse is right for you.
Frequently Asked Questions
Radiesse Filler
No. Radiesse is a temporary, biodegradable filler. Results typically last 12 to 15 months before the body naturally metabolizes the calcium hydroxylapatite microspheres.
Most patients experience only mild discomfort during injection. Radiesse also contains lidocaine in its formulation, which helps reduce pain during and immediately after treatment.
Pricing depends on the treatment area and number of syringes needed to achieve your goals. Book a consultation at CLEO Clinic for a personalized quote based on your facial assessment.
Botox relaxes muscles to reduce dynamic wrinkles like frown lines, while Radiesse adds volume and stimulates collagen to correct static folds and volume loss. The two are often combined for comprehensive results.
Unlike hyaluronic acid fillers, Radiesse cannot be dissolved with hyaluronidase, which makes precise technique and dosing by an experienced injector especially important.
Downtime is minimal. Mild swelling, redness, or bruising at injection sites usually resolves within a few days, and most patients return to normal activities immediately.
Radiesse is not recommended for pregnant or breastfeeding women, individuals with active skin infections at the treatment site, or those with certain bleeding disorders, and it is not used in the lips.
