Radiesse vs. Juvéderm Filler: What’s the Difference?


Gravity-induced subcutaneous tissue redistribution, increased bone resorption, and declining tissue elasticity cause various ageing-related facial problems. 

Our most common problem with patients is volume loss in the face, which results in wrinkles, creases, and sagging. Even lips can become less defined and full-looking over time. 

One technique we could employ to restore younger-looking, firmer skin and appearance by replenishing lost volume is the use of dermal fillers.

In 1981, the FDA approved bovine collagen as the first injectable cosmetic component. The use of many injectable materials as cosmetic dermal fillers has just been approved. However, several important differences deserve attention.

What Dermal Filler Would Be Best For Me?

Although there are several fillers in Malaysia, calcium hydroxylapatite and hyaluronic acid fillers are the most often utilised ones. Why is that

Calcium Hydroxylapatite (Radiesse)

To make calcium-based fillers, calcium hydroxylapatite, a material that is naturally found in human bones, is added to an aqueous solution for injection. 

Radiesse is the most widely used calcium-based filler. It is an excellent way to restore volume loss since it promotes collagen production. However, employing it has a huge disadvantage. 

Radiesse cannot be removed if a patient is dissatisfied with the results or, more seriously, if a very little amount of the filler enters or compresses a blood vessel. The blockage of blood flow is an emergency. If the product is not removed, it may necessitate surgery and cause tissue necrosis.

Why We Recommend Calcium Hydroxylapatite (Radiesse)

  • Collagen and elastin fibres are encouraged to develop
  • For many patients, immediate benefits continue for a year or longer 
  • Prolonged enhancement of general skin quality

Hyaluronic Acid Fillers (Juvéderm)

The main precursor of collagen, hyaluronic acid (HA), is produced by our bodies normally. 

Nasolabial folds (deep lines that extend from the lips to the chin or from the mouth to the nose) and volume loss in the cheeks can be improved using HA dermal fillers, which are gel-based formulations (marionette lines). 

Juvéderm filler can be used to highlight the lips’ natural volume or define the lip border.

The risks of post-injection bruising and oedema are the same for HA fillers as for other dermal fillers. These come and go. 

HA fillers’ special advantage is that an enzyme may quickly dissolve them (hyaluronidase). This is important in the unlikely scenario of a vascular blockage or if a patient is unhappy with the results.

Why We Recommend Hyaluronic Acid Fillers (Juvéderm)

  • Produces rapid, natural advantages that may last up to six months
  • Replenishes moisture in the skin
  • Restores structural support and volume loss

Dermal filler-related adverse effects might occur even in the hands of expert practitioners. Working with a qualified injector and a product that allows for correction is the safest way to use dermal fillers. 


There are both pros and cons to these fillers. Hyaluronic acid fillers are generally considered safer and more effective than calcium-based fillers, but they may not last as long. 

Calcium-based fillers, on the other hand, may be more affordable but may not be as safe or effective as hyaluronic acid fillers. It is important to check with a professional who is experienced in performing both fillers to decide which is best for you. 

For additional information or how to determine which dermal filler is best for you, you may contact the experts that offer both Radiesse® and Juvederm®.

If you’re looking for a safe, reputable, and efficient cosmetic clinic to renew your skin, you’ve come to the right place. The CLÉO clinic is the leading aesthetics centre in Kuala Lumpur, Malaysia. Thread lifts, CO2 laser resurfacing, signature peels, and dermal fillers are among the cosmetic procedures we provide. Schedule a free appointment to discover more!