Quick Answer: Your first Rejuran treatment starts with a consultation to confirm which variant suits your skin, followed by numbing cream and a short session of fine micro-injections lasting 10 to 40 minutes. Most people describe the sensation as a mild pinch rather than pain. Small bumps and light redness are normal for a day or two, with no real downtime, and visible improvement in texture typically starts within the first week.
If you’ve already decided on Rejuran and just want to know what actually happens once you’re in the chair, here’s the realistic walkthrough — no surprises.
The Consultation Comes First
Every Rejuran treatment starts with a consultation, not a walk-in injection. Your doctor will look at your skin, ask about your main concerns, and confirm which variant — Healer, S, I, or HB — actually fits what you’re trying to address. This is also when you should mention:
- Any known fish or salmon allergy
- Current medications, especially blood thinners
- Pregnancy or breastfeeding
- Any recent other cosmetic procedures in the area
Being upfront here is what lets your doctor build a treatment plan around your actual skin, not a generic protocol.
Before Treatment: What Preparation Looks Like
There’s no elaborate prep required. You can arrive with your normal skincare and makeup — it will simply be cleansed off before treatment. If advised, avoid blood-thinning medication or supplements for a few days beforehand, since these can increase bruising. Numbing cream is applied about 30 minutes before injection to keep the session comfortable.
During the Treatment
Step 1: Cleansing and Numbing
The treatment area is cleansed, then a topical numbing cream is applied and left on for around 30 minutes before injection begins.
Step 2: The Injections
Once numbed, your doctor delivers Rejuran through a series of fine micro-injections spread evenly across the treatment area. Most patients describe the sensation as a mild pinch or something like a small ant bite — noticeable, but not painful. The injection portion itself typically takes 10 to 40 minutes depending on the area and variant used.
Step 3: Massage and Cooling
After injection, your doctor may gently massage each point to evenly distribute the product and help “flatten” any raised bumps. Some clinics finish with a cooling step — an ice pack, cryotherapy, or LED light — to calm the skin and support faster recovery.
After Your Treatment
The First 24–48 Hours
Small red bumps at each injection point are completely normal and usually settle within a day or two. Mild swelling or pinpoint bruising can also happen, though it’s less common and typically resolves quickly on its own.
What You Can (and Can’t) Do Right Away
There’s no real downtime — most people go straight back to their day. A few simple things help recovery along:
- Avoid makeup for the first few hours, sometimes the rest of the day if advised
- Use a gentle cleanser and a light moisturiser rather than active ingredients
- Skip saunas, intense exercise, and direct heat for 24–48 hours
- Apply sunscreen daily, since freshly treated skin is a little more sensitive to sun
When Will You Actually See Results?
This is the part worth setting expectations for properly:
| Timeframe | What’s Happening |
|---|---|
| Day 1–2 | Small bumps and mild redness settle |
| Day 5–7 | Skin often starts to feel noticeably smoother |
| Week 2 | Hydration and texture improvement becomes more visible |
| Weeks 3–4 | Ready for your next session, if you’re doing the full course |
| After full course (3–4 sessions) | Cumulative improvement in texture, firmness, and scarring |
Rejuran works by triggering your own collagen production, not by adding anything artificial — so results build progressively rather than transforming your skin overnight. One session is a start, not the full picture.
Is It Normal to Feel Bumpy Right After?
Yes. The small, raised bumps you’ll feel immediately after treatment are simply the injected product sitting under the skin — they’re expected, not a sign anything went wrong, and they flatten out on their own (helped along by the post-injection massage) within a day or two.
Frequently Asked Questions
Does the first Rejuran session hurt? Most people describe it as a mild pinch or pressure, similar to a small ant bite, rather than actual pain. Numbing cream is applied beforehand specifically to keep this comfortable.
How long does a Rejuran appointment take in total? Including numbing time, expect around 45 minutes to just over an hour for your full appointment, though the injection itself is much shorter — typically 10 to 40 minutes.
Can I wear makeup right after treatment? It’s best to avoid makeup for at least a few hours after treatment, sometimes the rest of the day depending on your doctor’s advice, to reduce irritation risk at the injection sites.
Will I look bumpy or bruised afterward? Small bumps and mild redness are common and typically settle within a day or two. Bruising is less common but can happen occasionally, and also resolves on its own.
How soon can I go back to work or my normal routine? Immediately, in most cases. Rejuran has no real downtime — you can return to work and daily activities the same day, avoiding only intense exercise, saunas, and direct heat for the first 24 to 48 hours.
Do I need to come back for more sessions? Yes, for full results. A single session offers a starting improvement, but most people need a course of 3 to 4 sessions spaced about 4 weeks apart for the complete, cumulative effect.
Bottom Line
Your first Rejuran appointment is less intimidating than the research phase makes it feel: a proper consultation, a short session of numbing and fine micro-injections, some normal bumps and redness that settle within a couple of days, and no real downtime. The only thing that takes patience is the results themselves, since Rejuran works with your body’s own collagen production rather than delivering an instant change. For the full picture on the treatment itself, see our Rejuran treatment page, or book a consultation at CLEO Clinic to get started.
