Which Treatments Work on Wrinkles?

woman treating wrinkles

As we get older, we see the fine and coarse wrinkles, brown spots, mottled pigmentation, and signs of loss of elasticity that appear on our faces. These physical indicators are commonly targeted by people who invest thousands of dollars in skin treatment products, but how effective are these interventions?

Many advertised wrinkle treatments have not been tested or shown not to work, so it’s best to avoid those. However, here are seven things that actually work. 

1. Topical medication

Active formulations applied topically is one of the most effective ways to fight wrinkles. For example, a 2017 study found that daily application of 0.1 percent Topical wrinkle removal cream for 20 months reduced fine lines and wrinkles, increased the skin’s elasticity, and increased skin hydration.

The topical medication  should be applied in the morning (and sunscreen should be applied on top of it) for the best results. It should be used only on the face area with wrinkles and should not be applied to the eyelid area, as it can cause irritation or dryness.

2. Microneedling

Microneedling is great for acne scars, however, we can also use this treatment for eliminating fine lines and wrinkles. This treatment can be great for restoring elasticity to the skin and minimizing pesky fine lines and wrinkles. Since this is minimally invasive, almost no downtime is required to recover from the procedure.

3. Chemical Peels

Chemical peels remove the top layer of the skin and stimulate new skin growth. As a result, chemical peels can cause skin cells to shrink and produce smoother skin with fewer wrinkles.

Chemical peels can be done as a stand-alone treatment or as part of a series of treatments. Chemical peels can have side effects, so it’s best to begin chemical peels with a low concentration of mild acid and increase the concentration or frequency of chemical peels slowly over time.

4. Nonablative Laser Treatments

Nonablative laser treatments use lasers that are low enough energy to leave the skin’s outer layer intact. That means these treatments don’t damage the skin as much as ablative laser treatments, which remove the top layer of the skin.

Non Ablative laser treatments reduce the appearance of fine lines and wrinkles around the eyes and wrinkles around the mouth. They can also improve skin tone and texture and increase skin elasticity.

5. Profhilo

The treatment contains a high concentration of Hyaluronic Acid, making it great for those lacking volume to plump their face and improve elasticity looking fresher and younger. While this is newer on the market in terms of treatment, Profhilo has shown great results in usage.

The possibilities of this formula can only improve from here. The product does take time to fully set in. The magic of Profhilo is that your body learns to produce its own collagen in response to the shot. This takes about 4 to 6 weeks and can stay in your body for many weeks or months after.


As we get older, it’s natural for fine lines, wrinkles, mottled pigmentation, and loss of elasticity to occur. While most of us are resigned to this fact, we can fight some of the signs of aging with delicious and nutritious foods, topical treatments, chemical peels, non ablative laser treatments, and prescription medications.

CLÉO Clinic is a premium aesthetics practice based in Kuala Lumpur, Malaysia. We offer dermatology/body treatments like acne scarring, acne treatment, hair rejuvenation, vaginal tightening, HIFU lifting, and fat-freezing cryolipolysis. Try our chemical peels treatment in Kuala Lumpur to treat wrinkles! Get in touch with us to book an appointment!