• Aesthetic treatments • 4 min read

Plinest vs Newest vs Plinest Fast vs Plinest One: Which Is Right for You?

M.D.(MMA) Professional Diploma in Aesthetic Medicine (MAHSA University) Founder and Medical Director of Cléo Clinic . Living by the motto “Own your Appearance, Breed your Confidence”, Dr Raimie is a true believer of the power of transformation.

Table of Contents

Plinest is a family of polynucleotide skin boosters from Mastelli, Italy. Plinest is the standard polynucleotide gel for the face, neck and décolletage. Newest adds hyaluronic acid for extra hydration. Plinest Fast is another gel in the range, and Plinest One is designed for larger body areas, such as the abdomen, thighs and arms. The right variant depends on the area, your skin concern and your doctor’s assessment. For the full overview, see our Plinest injection page.

Mastelli sells several Plinest products, and their names are easy to confuse. This simple guide explains what each one is generally used for, so you know what to ask at your consultation.

Plinest vs Newest vs Plinest Fast vs Plinest One at a Glance

Product Main ingredient Typical use
Plinest Purified polynucleotides (PN-HPT) Face, neck and décolletage for skin quality and hydration
Newest Polynucleotides plus hyaluronic acid Hydration and skin quality, where extra hydration is wanted
Plinest Fast Polynucleotide gel, with its own formulation details Skin quality and hydration. Check the product sheet for specifics.
Plinest One Polynucleotide gel for body use Larger body areas, such as the abdomen, thighs, arms and décolletage

Plinest

Plinest is the standard polynucleotide gel in the range. It is used intradermally to support skin quality, elasticity and hydration on the face, neck, décolletage and hands. It does not contain hyaluronic acid.

Newest

Newest is a polynucleotide gel that also contains hyaluronic acid. The added hyaluronic acid is intended to boost hydration alongside the polynucleotide effect. It suits people who want extra hydration, although your doctor will decide if it is right for your skin.

Plinest Fast

Plinest Fast is a polynucleotide gel from the same range, used for skin quality and hydration. Its exact formulation and clinic positioning should be confirmed on the product information your clinic uses, rather than assumed from the name.

Plinest One

Plinest One is designed for larger body areas, including the abdomen, buttocks, thighs, arms and décolletage. It is also marketed for early laxity and stretch marks. Distributors list a multi-session protocol, but the number of sessions should be set by your doctor.

Plinest Eye

Plinest Eye is a separate variant for the delicate under-eye and eyelid area. If your concern is the eye area, read our tear trough filler guide and dark circles guide first, since not every dark circle responds to a skin booster.

How to Choose

  • Face and neck skin quality: standard Plinest is the usual starting point.
  • Extra hydration on the face: ask about Newest.
  • Body areas or stretch marks: ask about Plinest One.
  • Under-eye area: ask about Plinest Eye.

A doctor should assess your skin before choosing a variant, because the area, skin thickness and goals all matter.

Plinest vs Rejuran

If you are also comparing Plinest with Rejuran, read our Plinest vs Rejuran guide.

Frequently Asked Questions

Is Newest stronger than Plinest?

It is not stronger. It is a different formulation, and the added hyaluronic acid is intended to add hydration.

Can I use Plinest One on my face?

Plinest One is marketed for body areas. Ask your doctor which variant is suitable for the face.

Do I need one variant or several?

Some people use one, and others combine variants for different areas. Your doctor will set the plan.

To find out which Plinest variant suits you, contact CLEO clinic or read about our doctors.

Disclaimer: The information on this page is for educational and informational purposes only and does not constitute medical advice or establish a doctor-patient relationship. Plinest products are medical injectables and must only be administered by a qualified doctor. Product details can change, so check the current product information. Individual results vary. Please consult a healthcare professional for a medical assessment before treatment.